What does the Beyond-Use Date (BUD) indicate for a compounded preparation?

The Beyond-Use Date (BUD) is a critical concept in the field of compounded sterile preparations, as it defines the maximum time a compounded preparation can be stored and still be considered safe and effective for use. This date is determined based on various factors, including the type of preparation, storage conditions, and stability studies. The BUD takes into account the degradation of the active ingredients and the potential for microbial contamination, thus ensuring that the compounded product maintains its quality and safety for the duration specified.

In terms of the options provided, focusing on the maximum storage time after compounding captures the essence of what the Beyond-Use Date signifies: it is fundamentally about ensuring the integrity of the compounded medication over time. This critical indicator helps healthcare professionals make informed decisions on when to discard a compounded preparation to avoid potential harm to patients.