What is the required number of air changes per hour for an ISO Class 6 environment?

The required number of air changes per hour for an ISO Class 6 environment is critical for maintaining sterility and controlling airborne contamination. ISO Class 6 environments are typically used in pharmaceutical compounding and require a specific level of cleanliness and air quality.

For an ISO Class 6 space, it is generally recommended to have between 90 to 180 air changes per hour. This range ensures that any contaminants introduced into the environment are rapidly diluted and removed, thereby maintaining the sterile conditions necessary for compounding sterile preparations. Proper airflow and air changes help minimize the risk of microbial contamination and contribute to the overall safety and efficacy of compounded medications.

In contrast, other choices suggest a higher or lower number of air changes, which would not meet the necessary requirements for maintaining an ISO Class 6 environment and could compromise the integrity of the preparations being compounded.