What should be done if a compounded sterile preparation has an unexpected appearance?

If a compounded sterile preparation has an unexpected appearance, it is crucial to prioritize patient safety and product integrity. Reporting and not administering the preparation ensures that any potential issues can be assessed thoroughly. Unexpected changes in appearance, such as cloudiness, discoloration, or particulate matter, may indicate contamination or degradation of the product, which could pose significant risks to patients if used.

In this context, the appropriate action is to halt any plans for administration and inform the relevant personnel, such as a pharmacist or supervisor. This allows for an investigation into the cause of the unexpected appearance and ensures that the preparation is evaluated properly before considering its use again. Acting cautiously in cases of uncertainty is a vital component of maintaining safe practices in any healthcare setting, especially with sterile preparations.