Which of the following is NOT a PEC device?

The correct choice is the refrigerator, as it does not qualify as a Primary Engineering Control (PEC) device. PECs are designed to provide an aseptic environment for the preparation of compounded sterile products by controlling the airflow and minimizing contamination risks.

A laminar airflow workbench (LAFW) is a type of PEC that uses a unidirectional airflow to create a sterile work area, protecting the compounding process from airborne contaminants. Similarly, both the biological safety cabinet (BSC) and the compounding aseptic isolator (CAI) serve as PECs by providing a controlled environment that ensures sterility during compounding processes by using high-efficiency particulate air (HEPA) filters to filter out particulates.

In contrast, a refrigerator is not designed to provide an aseptic working environment; it is used primarily for the storage of drugs and preparations under controlled temperature conditions. While refrigeration is crucial for maintaining the integrity of certain medications, it does not facilitate the sterile compounding process itself and therefore is not considered a PEC device.