Which of the following substances is Daptomycin compatible with?

Daptomycin is an antibiotic that requires careful consideration regarding its compatibility with intravenous solutions. When preparing Daptomycin for administration, it's crucial to choose diluents that will not cause degradation or precipitation of the drug, which could compromise its efficacy and safety.

The compatibility of Daptomycin with 0.9% sodium chloride injection stems from the stability of the drug in a normal saline environment. This solution maintains a neutral pH and is isotonic, making it an appropriate choice for reconstitution and dilution of Daptomycin. The chemical environment of 0.9% sodium chloride does not favor instability or precipitation of the drug, allowing for safe and efficient administration to patients.

In contrast, other diluents listed, such as dextrose-containing solutions, distilled water, and phosphate buffers, may lead to interactions that compromise the drug's stability. Dextrose can create an osmotic environment unsuitable for Daptomycin, potentially resulting in precipitation. Distilled water lacks the necessary tonicity, which may also lead to destabilization of the drug. Phosphate buffers, while commonly used for various medications, may not provide the pH stability required for Daptomycin, and therefore, are not recommended.

Understanding the